Pyridines and derivatives
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- (2)
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- (1)
- (1)
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- (8)
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- (1)
- (1)
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- (1)
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- (1)
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- (1)
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- (12)
- (1)
- (1)
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- (1)
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Filtered Search Results
TARGETMOL CHEMICALS INC S-Vamicamide 1MG
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Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. (S)-Vamicamide is a novel anticholinergic compound.Vamicamide increases spontaneous locomotor activity in mice at 32 mg/kg or higher (p.o.) and inhibits tonic convulsions in mice at 100 mg/kg.13483-86-1 Purity 99.76%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC SID 125240931 | 701245-29-6 | 98.8% | 388.48 | 25 MG
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SID 125240931 is a modulator of fluorogen activating proteins (FAPs). It functions by interfering with the binding interaction between fluorogens and FAP.
- Interferes with the binding between fluorogens and FAP.
- For research use only.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Cleaved-Caspase 3 An | 10UL
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Cleaved-Caspase 3 An | 10UL
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Medchemexpress LLC USP7-IN-13 | 2305046-93-7 | 91.9% | 420.50 | 100 MG
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USP7-IN-13 (Compound 101) is a USP7 inhibitor with an IC50 value of 0.2-1 μM, which can be used for the study of multiple myeloma.
- USP7 inhibitor with an IC50 value of 0.2-1 μM.
- Useful for studying multiple myeloma.
- Active in cancer research.
- Targets deubiquitinase (DUBs).
- Applicable in blood or cardio-cerebrovascular disease research.
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Medchemexpress LLC Heptamidine dimetha | 25MG
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Heptamidine dimetha | 25MG
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![Medchemexpress LLC N-[4-(diethylamino)phenyl]-5-methyl-3-phenylisoxazole-4-carboxamide | 544681-96-1 | 99.2% | 349.43 g/mol | C21H23N3O2 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000245359.png-250.jpg)
Medchemexpress LLC N-[4-(diethylamino)phenyl]-5-methyl-3-phenylisoxazole-4-carboxamide | 544681-96-1 | 99.2% | 349.43 g/mol | C21H23N3O2 | 25 MG
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GATA4-NKX2-5-IN-1 is a research-grade small molecule inhibitor that disrupts the transcriptional synergy between GATA4 and NKX2-5, used to study cardiac transcription factor interactions and hypertrophic signaling pathways. The compound is supplied as a solid with high reported purity and is intended for in vitro research applications.
- Inhibits GATA4-NKX2-5 transcriptional synergy (IC50 = 3 μM).
- High purity (≈99%) suitable for in vitro research.
- Supplied in small-molecule quantities for assay and screening use.
- Molecular formula C21H23N3O2; molecular weight 349.43 g/mol.
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TARGETMOL CHEMICALS INC ochracin 25MG
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Also available in 1 mL, 5 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. (S)-(+)-ochracin (8-hydroxy-3-methyl-3,4-dihydroisochromen-1-one) is a marine derived natural products found in Helicascus kanaloanus. Purity 90%
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Medchemexpress LLC (R)-(-)-Gossypol acetic acid | 866541-93-7 | C32H34O10 | 50 MG
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(R)-(-)-Gossypol acetic acid is the levorotatory isomer of the natural product Gossypol. It binds to Bcl-2, Mcl-1, and Bcl-xL proteins with high affinity, showing potent activity against head and neck squamous cell carcinomas (HNSCC) cell lines in vitro. It induces apoptosis in HNSCC tumor cells with functional p53 and also kills tumor cells with mutant p53 via a different mechanism.
- Binds to Bcl-2, Mcl-1, and Bcl-xL proteins
- More potent than (+)-Gossypol in inhibiting cell growth and inducing apoptosis
- Exhibits greater growth inhibition relative to (±)-Gossypol than (+)-Gossypol in UM-SCC-6 and UM-SCC-14A cell lines
- Shows potent activity against head and neck squamous cell carcinomas (HNSCC) cell lines in vitro
- Induces apoptosis in HNSCC tumor cells with functional p53
- Kills tumor cells with mutant p53 via a different mechanism
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Medchemexpress LLC Thiobencarb | 28249-77-6 | 99.98% | 1 ML
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Thiobencarb is an herbicide that can reduce growth, photosynthetic activity, and the amount of Rieske iron-sulfur protein in the diatom Thalassiosira pseudonana. It is provided as a ready-to-use solution for laboratory applications.
- Purity: 99.98%
- Supplied as 1 mL of 10 mM solution in DMSO
- Storage at -20°C, protect from light
- In solvent storage at -80°C for 6 months or -20°C for 1 month (protect from light)
- CAS number: 28249-77-6
- Molecular weight: 257.79
- Chemical formula: C12H16ClNOS
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Apexbio Technology LLC SU5614 1055412-47-9 25mg
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SU5614 (CAS 1055412-47-9) is a small molecule inhibitor targeting protein tyrosine kinases notably FLT3 with an IC50 of 100 nM Tyrosine kinases modulate diverse cellular signaling pathways via phosphorylation events In vitro studies have shown that SU5614 induces growth arrest and apoptosis in c-kit-expressing leukemia cell lines such as Kasumi-1 M-07e and UT-7 by inhibiting SCF-induced tyrosine phosphorylation of c-kit In vivo SU5614 reduces vascular endothelial growth factor (VEGF) levels in bronchoalveolar lavage fluid in murine models implicating its potential in studying VEGF-related pathophysiology such as airway inflammation SU5614 is currently limited to preclinical research applications
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Medchemexpress LLC Mastoparan X | 72093-22-2 | 98.7% | 1555.97 | 5 MG
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Mastoparan X is a GTP-binding regulatory protein (G protein)-activating peptide, and a tetradecapeptide derived from wasp venom. It functions by directly activating G proteins that couple to phospholipase C, leading to secretion from various types of cells. This product is for research use only and not sold to patients.
- Activates GTP-binding regulatory proteins (G proteins).
- Derived from wasp venom as a tetradecapeptide.
- Directly activates G proteins that couple to phospholipase C.
- Induces secretion from various cell types.
- Interacts with phospholipid bicelles.
- Increases cell permeability to cations.
- Disrupts electrolyte balance and causes cell lysis.
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Selleck Chemical LLC PFI-2 HCl
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PFI-2 is a potent selective and cell-active lysine methyltransferase SETD7 inhibitor with Ki (app) and IC50 of 0 33 nM and 2 nM 1000-fold selectivity over other methyltransferases and other non-epigenetic targets
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Selleck Chemical LLC Zanamivir S3007-1g
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Zanamivir (GG167 GR 121167X) is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus
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Medchemexpress LLC Cot inhibitor-2 | 915363-56-3 | 99.65% | 539.43 | 5 MG
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Cot inhibitor-2 is a potent, selective, and orally active cot (Tpl2/MAP3K8) inhibitor with an IC50 of 1.6 nM. It inhibits TNF-α production in LPS-stimulated human whole blood with an IC50 of 0.3 μM.
- Potent, selective, and orally active cot (Tpl2/MAP3K8) inhibitor.
- Inhibits TNF-α production.
- Demonstrated Cmax of 517 ng/mL (0.89 μM) and AUC of 4841 ng h/mL in rats with 100 mg/kg dosing.
- Inhibits LPS-induced TNF-α production by 83% at a 25 mg/kg oral dose in Sprague-Dawley rats.
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Medchemexpress LLC Eurycomanone | 84633-29-4 | MFCD31726288 | 1 MG
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Eurycomanone, also known as Pasakbumin A, is a natural quassinoid that increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis. It has been shown to significantly increase testosterone production dose-dependently. Molecular docking studies indicate that Eurycomanone binds at different sites than some other inhibitors and can improve inhibition of aromatase in reducing estrogen production. This product is intended for research and analytical applications.
- Increases spermatogenesis
- Inhibits phosphodiesterase and aromatase
- Significantly increases testosterone production
- Suitable for research and analytical applications
- Demonstrates improved inhibition of aromatase in reducing estrogen production
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